N,N-DIMETHYL-1-(PIPERIDIN-4-YL)METHANAMINE 2HCL - Names and Identifiers
N,N-DIMETHYL-1-(PIPERIDIN-4-YL)METHANAMINE 2HCL - Physico-chemical Properties
Molecular Formula | C8H19ClN2
|
Molar Mass | 215.166 |
Storage Condition | Inert atmosphere,Room Temperature |
N,N-DIMETHYL-1-(PIPERIDIN-4-YL)METHANAMINE 2HCL - Introduction
N,N-Dimethyl(4-piperidinyl)methanamine dihydrochloride (also known as DMAP) is an organic compound with the chemical formula C9H14Cl2N2 and a molecular weight of 218.12. The following is an introduction to the nature, use, method and safety information of DMAP:
Nature:
1. Appearance: DMAP is usually a white crystalline solid.
2. Solubility: DMAP soluble in water, alcohol and ether and other common organic solvents.
3. Thermal stability: DMAP is relatively stable at high temperatures, but long-term heating will cause decomposition.
Use:
1. Catalyst: DMAP is often used as a catalyst in organic synthesis, and plays an important role in esterification, acylation, amidation and other reactions.
2. Drug synthesis: DMAP can be used to synthesize a variety of drugs, such as penicillin drugs, beta blockers, etc.
3. Dyes and coatings: DMAP can also be used in the synthesis of dyes and coatings.
Method:
The preparation of DMAP generally through the following steps:
1. Methylpiperidine hydrochloride is obtained by reacting methylpiperidine with hydrochloric acid.
2. Reaction of methylpiperidine hydrochloride with dimethylamine chloroformate to give 4-(dimethylaminomethyl) piperidine.
Safety Information:
1. DMAPP is generally considered to be relatively safe under normal conditions of use, but it is still necessary to pay attention to contact and inhalation.
2. Contact DMAP, avoid direct contact with the skin and eyes, such as contact occurs, should immediately rinse with plenty of water.
3. During use, pay attention to a well-ventilated working environment to prevent inhalation.
4. DMAP is a chemical and should be stored in a dry, cool, ventilated place, away from fire and oxidant.
Please note that DMAP is a chemical and should be used in a laboratory or suitable environment and operated in accordance with relevant safety procedures.
Last Update:2024-04-09 15:17:53